Roxy Withdrawal Symptoms

Roxy is the street name for the drug oxycodone. It is derived from the brand name of the medication, Roxicodone. Roxy pills generally come in 15 or 30 mg pills. It is an immediate release form of oxycodone, unlike the time-release form of the drug: OxyContin. Roxies are pure form of oxycodone; they do not contain ibuprofen, acetaminophen, or aspirin, like other oxycodone-containing products (i.e. Percodan, Percocet, and Tylox).

Roxy, or oxycodone, is a powerful, narcotic analgesic (painkiller). It is a semi-synthetic opioid. Roxy is generally prescribed for moderate to severe pain. In sufficient doses, oxycodone produces a feeling of euphoria.

Roxies are part of a highly addictive class of drugs. These drugs, known as opiods, mimic natural painkilling neurotransmitters in the brain, which is what creates the “high” when they are used. In response to long term use of opiates, the brain produces less of these substances, which causes roxy withdrawal to be very painful.

Roxy withdrawal results when a person becomes “tolerant” to roxies.  Tolerance is when the body adapts to regular drug use over a long period of time. Eventually, it takes more and more of the drug to produce the original effect. This is what happens to long term roxy users. Their bodies expect the pills. When roxy use is stopped or the dose is significantly reduced, the body reacts in a physical way. This is known as roxy withdrawal.

Withdrawal from roxies can cause a number of unpleasant symptoms. Common roxy withdrawal symptoms include extreme pain, tremors, muscle cramps, sweating, chills, rapid heartbeat, itching, restless leg syndrome, runny nose, sneezing, nausea, vomiting, diarrhea, and weakness. Withdrawal from roxies alone is not life-threatening, but it is extremely uncomfortable. Acute roxy withdrawal can last ten to fourteen days (depending on level of use.) Post-acute withdrawal from opiates lasts an indefinite amount of time, usually proportional to how long you have been abusing roxies. However, post-acute withdrawal from roxies is much less severe than acute roxy withdrawal and generally includes symptoms like insomnia, fatigue, and mild anxiety.

There are several medications on the market designed to treat acute roxy withdrawal symptoms. One of the most common medications is buprenorphine (brand name: Suboxone or Subutex). Buprenorphine has replaced methadone as the medication of choice to treat roxy withdrawal symptoms. This medication eliminates the worst of the acute roxy withdrawal symptoms. It is what is known as a long-acting, partial opiate receptor. It binds to the opiate receptors, but only activates them partially, whereas roxies are a full opiate receptor. The long half-life of buprenorphine reduces the risk of abuse.

Clonidine is another medication that is commonly used to treat roxy withdrawal symptoms. Clonidine mimics the hypotensive (blood pressure lowering) effects of roxies. It is helpful in treating common central nervous system roxy withdrawal symptoms like tachycardia (rapid heartbeat) and hypertension (high blood pressure). Clonidine also reduces sweating, hot and cold flushes, and general restlessness.

Benzodiazepines are another class of medications used to treat roxy withdrawal symptoms. Benzo’s are normally prescribed as anti-anxiety medications. These drugs can relieve symptoms of anxiety, restless leg syndrome, tremors, and insomnia.


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