Roxicodone’s main ingredient is oxycodone hydrochloride. It is the active component of the medication. It is a narcotic painkiller of the opiate class. However, that is not the only ingredient in a pill of Roxicodone. Roxicodone ingredients also include certain binders, fillers, and disintegrates.
Roxicodone Ingredients: What are binders, fillers, disintegrates?
When a generic drug is made, the only ingredient that they must include is the active ingredient. There are other requirements of generic drugs as well. They must be identical in dose, strength, route of administration, safety, efficacy, and intended use.
Binders, fillers, and disintegrates can be, and often are, different between different types of generic drugs. The binders are what make the Roxicodone ingredients stick together when the pill is pressed down to make the pill. Common binders are povidone, xanthan gum and carbopol.
Fillers are used to take up space to make the pill a certain size and shape. Common fillers include lactose, microcrystalline cellulose, corn starch, sugars (including sucrose, mannitol, sorbitol, fructose, and dextrose), whey and yeast.
Disintegrates are the Roxicodone ingredients that help the pill break down in your digestive system. Crospovidone, croscarmellose sodium, and gellan gum are commonly used as disintegrates.
Roxicodone Ingredients: Why does it matter?
Some people claim there is a big difference between different generic forms of Roxicodone, and they could be right. The FDA requires the bioequivalence of the generic product to be between 80% and 125% of that of the brand name product, so the generics could be as much as 25% different than the brand name drug. Some consumers have complained that they do not get the same kind of pain relief or experience different side effects from different forms of the drug.
Another group that is concerned about the different Roxicodone ingredients are the illicit users. This group is using the drug in a way that it is not prescribed: usually snorting, shooting, or smoking the pill instead of taking it orally. For the illicit user, Roxicodone ingredients can be very important. Since generics are only tested for bioequivalence for the route of administration they are intended for, different generics can have very different effect when they are consumed in another way.
Binders, fillers, and disintegrates can all effect how well a drug can be crushed- whether or not there are large chunks of the pill in the powder-before it is snorted or injected. Also, some Roxicodone ingredients will affect nasal absorption or how well a pill will “smoke.”
Most illicit users are partial to certain generic forms of Roxicodone because of the way they break down for use. They will search out certain forms of the pills for a better “high.” However, in the case of injection, ease of use is not the only concern. It can be very dangerous to inject certain Roxicodone ingredients. When something is injected, it does not get broken down by the liver or digestive system. It goes straight to the blood stream and some Roxicodone ingredients can damage veins or cause blockages.