The 5 Hardest Drugs to Kick

The 5 Hardest Drugs to Kick

When determining which drugs are the hardest drugs to kick, it is helpful to see which the most addictive drugs are. These two concepts are pretty much synonymous. This is because rate of dependence and severity of withdrawal symptoms have everything to do with trying to kick a nasty drug habit.

The following is a list of the 5 hardest drugs to kick, from least to greatest in difficulty. This list is based on a study put together by Dutch scientists who replicated a London study and devised a “dependency rating” that measures addictive potency of the biggest drugs out there. The scale of 0-to-3 shows how the hardest drugs to kick measure up.

#5 Crystal Meth 2.24

What makes crystal meth one of the hardest drugs to kick is that, like heroin and nicotine, meth also imitates dopamine, the reward chemical, and norepinephrine, the alertness chemical, causing your neurons to release more of both—all the while training your brain to want them more. But meth takes it a step further; it can damage dopamine- and norepinephrine-releasing neurons, which leads to a drastic decrease in their production, which makes you crave meth even more.

#4 Methadone 2.68

Basically legalized heroin, methadone is highly addictive because the way it works and is used as a treatment for heroin addiction is to build dependence. And in the case of methadone, dependence is the same as addiction.

Now, it is debatable whether methadone belongs at #4 on the list of hardest drugs to kick because, in my personal experience and from others who have shared their methadone experiences with me, I find it to be a much nastier drug to kick than heroin.

The withdrawals are hell on earth. Heroin withdrawal is said to be more acute but lasts for a much shorter period of time, about a week depending on usage and your body chemistry. Methadone withdrawal is really just as bad when it comes to the severity of the symptoms. What makes methadone harder to kick than heroin is that the withdrawal symptoms last for a longer period of time. And I mean a lot longer. For me it was about a month and a half before I started to feel normal again. Some people experience methadone withdrawal for even longer than that. Because of this, many people return to their drug use to feel better again, making methadone one of the top 5 hardest drugs to kick.

#3 Nicotine 2.82

Nicotine mimics chemicals that stimulate the “reward system” in the brain and then actually replaces them. Nicotine addiction occurs because this replacement causes your brain to make less of the naturally occurring good stuff and so the brain now needs nicotine to maintain normal functioning.

Statistics don’t lie: nicotine proves to be one of the hardest drugs to kick by the sheer number of nicotine addicts in the US: 50,000,000; and one in every five deaths nationwide are the result of smoking.

And actually, there is a tie for spots 2 and 3 which many may find surprising. That’s right, the study found that nicotine is just as hard to kick as crack cocaine.

#2 Crack Cocaine 2.82

Although crack is comprised of cocaine, smoking processed crack causes a faster, higher rush that lasts for less time than powder coke. The intensity of the crack high combined with the efficient method of use—smoking—are the big reasons why crack is number two in the top 5 hardest drugs to kick.

Crack addiction is dramatically higher than that of snorted cocaine powder. In 2010, there were an estimated 500,000 active crack cocaine addicts in the United States. And although not physical in nature, the psychological withdrawal symptoms from crack are intense and terrifying: hallucinations, severe anxiety, and depression.

#1 Heroin 2.89

Again, statistics show how heroin is one of the hardest drugs to kick. In the US in 2003, an estimated 281,000 people sought treatment for heroin addiction, and according to the National Institute on Drug Addiction, 23% of people who try heroin become full on addicts.

Heroin is easy to get hooked on. It reduces pain while at the same time causes pleasure. Who wouldn’t want to feel this way? By injecting, snorting or smoking heroin, you are training your brain to make you crave it. After you are physically dependent on heroin, the nasty withdrawal symptoms are enough to keep you coming back for more. It’s clear that heroin is the hardest drug to kick once you’re hooked on it.

 Honorable Mention(s):

Alcohol and Benzodiazepines

Both alcohol and benzos (such as Valium and Xanax) are also some of the hardest drugs to kick because the withdrawal symptoms that result from trying to kick cold turkey are very intense and even possibly fatal. People who stop using alcohol and benzos can experience hallucinations, sweats, anxiety, tremors, seizures, cardiac arrest and even death as a result of these symptoms.





How Heroin and Alcohol Killed Cory Monteith

How Heroin and Alcohol Killed Cory Monteith


The combination of heroin and alcohol is currently a hot news topic with the recent accidental death of actor and Glee cast member Cory Monteith.

Tragedy strikes

Saturday, July 6 the Vancouver police said in a news conference Saturday evening that Cory Monteith was found at noon on the hotel’s 21st floor. He had checked into the Fairmont Pacific Rim hotel and had been expected to check out Saturday. When Monteith missed his checkout time at noon, hotel staff went to his room and found him, deceased.

Past Struggles

Monteith told Parade magazine in 2011 that he was “out of control” as a teen. He revealed that at age 13, he drank, smoked pot and skipped school in Victoria, British Columbia, after his parents divorced. By 16, his drug use had escalated. He was “doing anything and everything, as much as possible.” At 19, he entered rehab for the first time.

On March 31, 2013, the media announced that Monteith had admitted himself into a treatment facility for substance addiction. His treatment was completed on April 26, 2013.

Autopsy and Findings

An autopsy was completed by the British Columbia Coroners Service on July 15. The autopsy report stated that Monteith died from “a mixed drug toxicity” consisting of heroin and alcohol, and that his death appeared to have been accidental.

Heroin and Alcohol: a Deadly Combination

The drugs of abuse may give the user a feeling of pleasure, but it is important to remember that they are toxic substances. The vast majority of drug overdose cases involve the use of more than one drug. In 2003 the Drug Abuse Warning Network reported an average of 2.7 drugs in fatal overdose cases. Importantly in these cases, no single drug is usually present at a lethal dose. Rather it is the synergistic effect (think: 1+1=3) of the combining of drugs that is lethal. For example, a combination of heroin and alcohol can be especially dangerous. Heroin and alcohol both suppress breathing, but by different mechanisms.

Heroin is the cause for more deaths by overdose than any other single drug. The majority of these deaths ultimately result from respiratory failure. A toxic dose of heroin increases the inhibitory effect of GABA, which causes breathing to slow and eventually stop.

Alcohol overdoses occur predominantly in two ways. First, a high intake of alcohol causes unconsciousness. At high levels, it can also cause breathing to slow or cease. Second, the body tries to rid itself of unabsorbed alcohol by emptying the stomach. If a person vomits while they are unconscious, they may inhale the vomit and compromise their breathing or even drown.

Heroin and alcohol together is especially dangerous, experts say, because alcohol can exaggerate heroin’s effect on the central nervous system.

How Heroin and Alcohol Killed Cory Montieth

As with other cases where heroin and alcohol were involved, Cory’s death was likely an overdose of either alcohol, heroin or both, resulting in coma, brain damage and eventually death. Even if he had not taken a lethal amount of heroin, it proved to be deadly when he combined it with alcohol.

Drugs that depress that central nervous system slow the heartbeat, or in large enough doses, can stop it from beating entirely. Without oxygen-rich blood pumping to the body, brain cells become depleted and can die within minutes.

Heroin, a highly addictive opiate drug, is considered a depressant because of its effects sedating the central nervous system. Alcohol also functions as a depressant.

Combining these two depressants forms a deadly drug combination.







Q&A: Can Roxicodone interact with other medications or foods?

Like any other drug, Roxicodone can interact with other medications and food. It’s important to take note of these interactions before combining Roxicodone with other prescription medications. There are over 900 separate medications that can interact with Roxicodone. Roxicodone can also interact with certain foods. Here is a list of the major interactions of Roxicodone.

1. Alcohol: The combination of alcohol or medications containing alcohol, and Roxicodone can be deadly. Alcohol and Roxicodone interact in a way that potentiates the effect of both. When Roxicodone and alcohol are combined, their effects increase exponentially. 98% of reported opiate overdoses have included the co-use of alcohol and/or other central nervous system depressants.

2. Alvimopan: Roxicodone may increase the risk of serious alvimopan side effects. You should not take alvimopan if you have taken Roxicodone for each of the past seven days.

3. Antidepressants: Combining antidepressants with Roxicodone could increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing.

4. Antihistamines: Many antihistamines cause significant drowsiness and can cause serious problems when used in combination with other medications that cause drowsiness, such as Roxicodone. Taking an antihistamine with Roxicodone may also increase the risks of other side effects (such as constipation or difficulty passing urine).

5. Antipsychotics: Combining an antipsychotic medication with Roxicodone can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing.

6. Barbiturates: Combining a barbiturate with Roxicodone can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing.

7. Benzodiazepines: Taking Roxicodone in combination with a benzodiazepine might increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing.

8. Grapefruit Juice: Grapefruit blocks the effect of the enzyme CYP3A4 which is concentrated mostly in the liver, and it is responsible for the breakdown of certain drugs, including Roxicodone. This causes an increase in Roxicodone concentration, which can cause serious reactions.

9. Monoamine Oxidase Inhibitors (MAOIs): Combining Roxicodone with an MAOI can cause serious reactions. Do not use Roxicodone and an MAOI within 14 days of each other.

10. Muscle Relaxants: Taking Roxicodone with a muscle relaxant may increase the risk of side effects due to both medications.

11. Other Narcotics or Opioids: Use extreme caution when combining Roxicodone with other narcotics or opioids, as serious side effects could occur.

12. Sleep Medications: Roxicodone can cause significant drowsiness, and combining it with a sleep medication could lead to dangerous effects. In general, Roxicodone should not be used in combination with sleep medications.

This is by no means a comprehensive list of all the interactions between Roxicodone and other medications or food. Medication interactions are no joke, and with a powerful drug like Roxicodone, you could have some serious side effects, including difficulty breathing, coma, and death. Even some herbal medications can interact with Roxicodone, so take the necessary precautions! Your best bet is to check with your doctor or pharmacist before taking Roxicodone with anything else.



Alcohol and Roxy Addiction

Alcohol and Roxy Addiction


Alcohol and Roxy Addiction

What is Alcohol Addiction?

Alcohol addiction, or alcoholism, is a chronic, progressive disease that includes problems controlling your drinking, being preoccupied with alcohol, continuing to drink despite negative consequences, having to drink more to get the same effect or having withdrawal symptoms when you rapidly decrease or stop drinking.

What is Roxy Addiction?

Roxicodone or Roxy’s as they are known to people who abuse them, is a prescription painkiller that is made from oxycodone hydrochloride. Roxies are taken orally but can also be smoked or injected when melted down. Roxies give users feelings of intense euphoria along with increased energy and the belief that they can do more than ever before. Some other side effects of a roxy addiction are anxiety, muscle spasms, mood changes, nausea, convulsions, and respiratory problems.

Dual substance addiction is very common. Most people have a “drug of choice,” but if that isn’t available, they will seek some other high. Some people have different drugs of choice during different times in their lives. In college, they may abuse alcohol, then later they may be introduced to roxys or some other drug, and decide they like that better. Still others will take any drug and do not really have a preference.

The thing to remember about alcohol and roxy addiction is that addiction is addiction no matter what substance it is. I know people who have had a roxy addiction who think that once they kick that, they will be able to drink alcohol normally. I know other people who think that alcohol was their problem, and once they stop drinking, it’s ok to take prescription narcotics. This can be a dangerous way of thinking. An addiction is an addiction no matter what the substance, and for true recovery, an addict usually must stay away from all mind and mood altering chemicals.

An alcohol and roxy addiction together is more dangerous than either addiction alone. Overdose is much more common when you mix two substances together. Alcohol and roxies are both central nervous system depressants, so the combination can have serious and deadly consequences. Also, opiate withdrawal alone is generally not life threatening. If a healthy person is physically dependent on roxies, and then you take away the roxies, it will be painful, but they won’t die. However, alcohol is one of the most dangerous drugs to withdrawal from. This type of detox should always be carried out under the supervision of a medical professional. . Severe complications of alcohol withdrawal include seizures and delirium tremens (also called DTs). DT’s are characterized by rapid heartbeat, fever, and confusion, and, in a certain number of cases, result in death. If left unattended, patients suffering from alcohol withdrawal can suffer head injuries, lethal dehydration, heart attack or stroke and can choke on their own vomit.

It is important to understand that, in addiction, the drug DOESN’T MATTER. Whether you are suffering from alcohol and roxy addiction, roxy addiction alone, alcohol addiction, or addiction to any other substance, you should abstain from any and all mind altering substance. Thinking of alcohol as different than other drugs causes many people to relapse. One of two things usually happens: alcohol becomes the drug of choice, or they get bored of alcohol and go back to their drug of choice.

Alcohol and roxy addiction can be treated, and recovery is possible. The first step towards solving a problem is admitting there is a problem. If you are suffering from alcohol and roxy addiction, there are many resources that can help you. The first step is usually a safe, medical detox under the supervision of addiction professionals. This process is a lot more comfortable than trying to kick either addiction on your own. After that, there are many options for drug treatment that can help you find lasting recovery from alcohol and roxy addiction.